基本信息
职称：助理研究员
研究方向：新型免疫调节型抗肿瘤微纳米药物的设计、构建与功能评价
电子邮件：zjlqingdao@126.com
个人简介
张佳良，男，博士，毕业于上海交通大学。科研方面，作为核心成员参与国家自然科学基金项目1项，主持省厅级等课题3项；学术成果方面，以第一作者或通讯作者身份发表SCI论文12篇。此外，担任《Journal of Nanobiotechnology》《International Journal of Pharmaceutics》等国际知名期刊审稿人，同时兼任福建省药学会第七届药剂专业委员会委员。
主要科研项目
1.福建省自然基金面上项目，阿霉素和伊维菌素共递送纳米粒用于胞外ATP助力的肝癌化学免疫治疗的机制研究，2023.08至2026.08，主持。
2.福建省科技联合创新基金项目，特异性激活肿瘤浸润性树突状细胞ATP/P2X7通路的纳米佐剂增强化学免疫疗法的机制研究， 2022.10 至 2025.10，主持。
3.福建省卫生健康中青年骨干人才培养项目，微针辅助透皮的氟碳微乳凝胶增强皮肤鳞状细胞癌光动力疗效的研究， 2022.01 至 2024.12, 10万元，主持。
近五年发表的主要论文
1. Jialiang Zhang, Jinyu Zhang, Qiang Feng, Xin Jiang, Yong Yang, Wenhan Liu, Jianbin Xiao, Jukai Feng, Zhiyu Wang, Meiqi Pan, Jianmin Wang, and Jingfeng Liu. Purinergic Receptor Nanoimmunoamplifiers Potentiate Chemoimmunotherapy Efficacy in Hepatocellular Carcinoma. Biomaterials Research, 2025, 29, 0278.
2. Xuejiao Liang, Jialiang Zhang, Chi Zhang, Haojie Zhai, Ping Yang, and Ming Chen. Mesoporous Silica Coated Spicules for Photodynamic Therapy of Metastatic Melanoma. Journal of Nanobiotechnology, 2024, 22(1), 179-194.
3. Xianquan Feng, Jialiang Zhang, Lina Wu, Wanjing Lin, Zhihong Liu, Xin Zhou, Yang Qi, Zhenzhen Chen, Lingjun Zeng, Changqing Zheng, Xiaomu Hu, Qian Zhang, and Hongtao Song. Drug Self‐Delivery Nanocubes Enhance O2‐Economized Photodynamic‐Immunotherapy of Triple‐Negative Breast Cancer by Downregulating Wnt/β‐catenin Signaling. Advanced Healthcare Materials, 2023, 12(19), 2203019-2203034.
4. Jialiang Zhang, Qiang Feng, Jianbin Xiao, Jinyu Zhang, Jiao Lin, and Jianmin Wang. Microneedle-Assisted Transdermal Delivery of Perfluorotripropylamine-Based Oxygenated Emulsion Gel Loaded with 5-Aminolevulinic Acid for Enhanced Photodynamic Therapy of Cutaneous Squamous Cell Carcinoma. European Journal of Pharmaceutical Sciences, 2023, 188, 106493.
5. Zhenzhen Chen, Qian Zhang, Qinbiao Huang, Zhihong Liu, Lingjun Zeng, Lingna Zhang, Xu Chen, Hongtao Song, and Jialiang Zhang. Photothermal MnO2 Nanoparticles Boost Chemophotothermal Therapy-Induced Immunogenic Cell Death in Tumor Immunotherapy. International Journal of Pharmaceutics, 2022, 617, 1-15.
6. Wenhao Gao, Jialiang Zhang, Weifeng Wang, Zhihong Liu, Mulan Chen, Xiaomu Hu, Lingjun Zeng, Changqing Zheng, Hongtao Song, and Qian Zhang. Drug Self-Delivery Nanorods Enhance Photodynamic Therapy of Triple-Negative Breast Cancer by Inhibiting Oxidative Phosphorylation. International Journal of Pharmaceutics, 2022, 621, 121775.
