基本信息
职称 主治医师
职务 主治医师
研究方向：肿瘤生物大数据分析以及肺癌、食管癌的基础研究
电子邮件：wangpeiyuan18@163.com
个人简介
王佩元，男，博士。就读于哈尔滨医科大学临床医学本硕博连读，肿瘤学专业。主要研究图像处理、计算机视觉和机器学习。现为福建省抗癌协会肿瘤内科专委会第二届青委会委员；福建省医师协会胸外科分会第一届数字医学与应用学组委员；福建省医师协会胸外科分会第一届胸部肿瘤研究者学组委员；中国老年学和老年医学学会肿瘤康复分会委员。
主要科研项目
国家课题
主持国家自然青年基金课题“LncRNA EGOT-p53蛋白正反馈调节环路在食管鳞癌DNA损伤反应中的作用及分子机制研究” 2020.1-2023.12
省课题
主持省自然青年课题“lncRNA EGOT参与食管鳞癌DNA损伤反应的机制研究” 2020.1-2023.12
获奖经历
2022获得福建省抗癌协会科技进步三等奖。
近五年发表的主要论文
1. Wang F, Gao X, Wang P（并列一作）, He H, Chen P, Liu Z, et al. Immune Subtypes in LUAD Identify Novel Tumor Microenvironment Profiles With Prognostic and Therapeutic Implications. Front Immunol. 2022;13:877896.
2. Xu S, Wang P（并列一作）, Zhang J, Wu H, Sui S, Zhang J, et al. Ai-lncRNA EGOT enhancing autophagy sensitizes paclitaxel cytotoxicity via upregulation of ITPR1 expression by RNA-RNA and RNA-protein interactions in human cancer. Mol Cancer. 2019;18(1):89.
3. Wang P（一作）, Wang F, He H, Chen Y, Lin H, Chen P, et al. TP53 and CDKN2A mutations in patients with early-stage lung squamous cell carcinoma: an analysis of the correlations and prognostic outcomes. Ann Transl Med. 2021;9(16):1330.
4. Wang P（一作）, Zhang D, Lin X, Chen Y, He H, Chen P, et al. Purse-indigitation mechanical anastomosis vs. traditional mechanical anastomosis undergoing McKeown esophagectomy: a retrospective comparative cohort study. Ann Transl Med. 2022;10(16):903.
5. Zhang J, Wang P, Wan L, Xu S, Pang D. The emergence of noncoding RNAs as Heracles in autophagy. Autophagy. 2017;13(6):1004-24.
6. Xu S, Wang P, You Z, Meng H, Mu G, Bai X, et al. The long non-coding RNA EPB41L4A-AS2 inhibits tumor proliferation and is associated with favorable prognoses in breast cancer and other solid tumors. Oncotarget. 2016;7(15):20704-17.
7. Sui S, Zhang J, Xu S, Wang Q, Wang P, Pang D. Ferritinophagy is required for the induction of ferroptosis by the bromodomain protein BRD4 inhibitor (+)-JQ1 in cancer cells. Cell Death Dis. 2019;10(5):331.
8. Zhang J, Zhang J, Xu S, Zhang X, Wang P, Wu H, et al. Hypoxia-Induced TPM2 Methylation is Associated with Chemoresistance and Poor Prognosis in Breast Cancer. Cell Physiol Biochem. 2018;45(2):692-705.
9. He H, Wang F, Wang PY, Chen P, Li WWL, Perroni G, et al. Anatomical analysis of variations in the bronchus pattern of the left upper lobe using three-dimensional computed tomography angiography and bronchography. Ann Transl Med. 2022;10(6):305.
10. Chen P, Zheng Y, He H, Wang PY, Wang F, Liu SY. The role of endoscopic tumor length in resected esophageal squamous cell carcinoma: a retrospective study. J Thorac Dis. 2021;13(1):353-61.
11. He H, Chen P, Chen X, Wang PY, Liu SY, Wang F. Analysis of anatomical variations of the lingular artery of the left upper lobe using 3D computed tomography angiography and bronchography. J Thorac Dis. 2021;13(8):5035-41.
