基本信息

职称 主治医师

职务 主治医师

研究方向：肿瘤生物大数据分析以及肺癌、食管癌的基础研究

电子邮件：wangpeiyuan18@163.com

个人简介

王佩元，男，博士，主治医师，硕士生导师。就读于哈尔滨医科大学临床医学本硕博连读，肿瘤学专业，日本国立癌症中心访问学者。主要研究机器学习，食管癌，肺癌大数据筛查与临床诊疗。现为中国抗癌协会肿瘤缺氧生物学和临床应用委员；福建省抗癌协会肿瘤内科专委会第二届青委会委员；福建省医师协会胸外科分会第一届数字医学与应用学组委员；福建省医师协会胸外科分会第一届胸部肿瘤研究者学组委员；中国老年学和老年医学学会肿瘤康复分会委员。

主要科研项目

1.LncRNA EGOT-p53蛋白正反馈调节环路在食管鳞癌DNA损伤反应中的作用及分子机制研究 2020.1-2023.12，主持，国家自然青年基金课题

2.lncRNA EGOT参与食管鳞癌DNA损伤反应的机制研究 2020.1-2023.12，主持，福建省自然青年课题

获奖经历

1.2022获得福建省抗癌协会科技进步三等奖，第二完成人

近五年发表的主要论文

1.Wang P（一作）, Lei M, Chen Y, He H, Lin J, Lin H, Wei W, Chen P, Zhang D, Chen W, Zhou H, Gao P, Liu S, Wang F. Prognostic Factors and Outcomes in Elderly Esophagectomy Patients with Esophageal Cancer. Ann Surg Oncol. 2024 Mar;31(3):1553-1561.

2.He H, Wang P（并列一作）, Zhou H, Wei W, Lin J, Chen Y, Wang F, Liu S. The advantages of preoperative 3D reconstruction over 2D-CT in thoracoscopic segmentectomy. Updates Surg. 2024 Sep 29.

3.Wang P（一作）, Chen Y, Lei M, He H, Zhang D, Lin J, Lin H, Wei W, Chen P, Zhuang F, Chen W, Zhou H, Gao P, Liu S, Wang F. Comparison of neoadjuvant chemoimmunotherapy and neoadjuvant chemotherapy for resectable esophageal squamous cell carcinoma: a retrospective study with 3-year survival analysis. J Cancer Res Clin Oncol. 2024 Oct 25;150(10):477.

4.Wang P（一作）, Lei M, Weng G, Huang R, Lin H, Wei W, Chen Y, He H, Chen P, Zhang D, Chen W, Zhou H, Gao P, Liu S, Wang F. High-dose chemotherapy sensitizes locally advanced esophageal squamous cell carcinoma to PD-1 blockade for a higher pathological complete response rate and survival. Transl Oncol. 2023 Oct;36:101736.

5.Lei M, Wang P（并列一作）, Liu S, Wang F. ASO Author Reflections: Opting for the Most Appropriate Treatment Approach for Elderly Patients with Resectable Esophageal Cancer. Ann Surg Oncol. 2024 Apr;31(4):2517-2518

6. Wang F, Gao X, Wang P（并列一作）, He H, Chen P, Liu Z, et al. Immune Subtypes in LUAD Identify Novel Tumor Microenvironment Profiles With Prognostic and Therapeutic Implications. Front Immunol. 2022;13:877896.

7. Xu S, Wang P（并列一作）, Zhang J, Wu H, Sui S, Zhang J, et al. Ai-lncRNA EGOT enhancing autophagy sensitizes paclitaxel cytotoxicity via upregulation of ITPR1 expression by RNA-RNA and RNA-protein interactions in human cancer. Mol Cancer. 2019;18(1):89.

8. Wang P（一作）, Wang F, He H, Chen Y, Lin H, Chen P, et al. TP53 and CDKN2A mutations in patients with early-stage lung squamous cell carcinoma: an analysis of the correlations and prognostic outcomes. Ann Transl Med. 2021;9(16):1330.

9. Wang P（一作）, Zhang D, Lin X, Chen Y, He H, Chen P, et al. Purse-indigitation mechanical anastomosis vs. traditional mechanical anastomosis undergoing McKeown esophagectomy: a retrospective comparative cohort study. Ann Transl Med. 2022;10(16):903.

10.Zhuang F, Lin J, Chen W, Chen X, Chen Y, Wang P, Wang F, Liu S. The prognostic significance of right paratracheal lymph node dissection numbers in right upper lobe non-small cell lung cancer. Updates Surg. 2024 Sep;76(5):1899-1908. doi: 10.1007/s13304-024-01778-7. Epub 2024 Feb 28.

11.Lin JP, Chen XF, Chen WJ, Wang PY, He H, Zhuang FN, Zhou H, Chen YJ, Wei WW, Liu SY, Wang F. Construction and validation of a risk-scoring model to predict lymph node metastasis in T1b-T2 esophageal cancer. Surg Endosc. 2024 Feb;38(2):640-647

12. Sui S, Zhang J, Xu S, Wang Q, Wang P, Pang D. Ferritinophagy is required for the induction of ferroptosis by the bromodomain protein BRD4 inhibitor (+)-JQ1 in cancer cells. Cell Death Dis. 2019;10(5):331.

13. He H, Wang F, Wang PY, Chen P, Li WWL, Perroni G, et al. Anatomical analysis of variations in the bronchus pattern of the left upper lobe using three-dimensional computed tomography angiography and bronchography. Ann Transl Med. 2022;10(6):305.

14. Chen P, Zheng Y, He H, Wang PY, Wang F, Liu SY. The role of endoscopic tumor length in resected esophageal squamous cell carcinoma: a retrospective study. J Thorac Dis. 2021;13(1):353-61.

15. He H, Chen P, Chen X, Wang PY, Liu SY, Wang F. Analysis of anatomical variations of the lingular artery of the left upper lobe using 3D computed tomography angiography and bronchography. J Thorac Dis. 2021;13(8):5035-41.