基本信息
职称:主治医师
职务:无
研究方向:肿瘤学
电子邮件:happygo1988@sina.com
个人简介
林城,男,放疗科主治医师,肿瘤学博士。博士毕业于福建医科大学,师从著名肿瘤学专家潘建基教授,目前主要从事恶性肿瘤的放化疗等,主要学术兼职为福建省抗癌协会第二届肿瘤内科专业委员会青委会委员。
近年来主要研究领域为鼻咽癌,专注于探讨EB病毒与鼻咽癌发生发展的关系和转移性鼻咽癌的诊疗,并注重基础研究的临床转化。作为项目负责人,主持省级课题2项、卫生厅课题1项、校级课题1项,累计经费大于30万;作为参与者,参与国家级课题3项。共发表SCI论著10余篇,以第一作者或共同第一作者发表SCI论著7篇,单篇被引频次大于80次,总影响因子大于25分。以第一作者发表中文核心期刊1篇,被引频次大于30次。
主要科研项目
(1)福建省卫生健康委员会,福建省卫生健康中青年骨干人才培养项目, 2020GGB010, EB病毒miR-BART8-3p调控FCHO1参与鼻咽癌免疫抑制的机制研究, 2021-01至2023-12, 8万元,在研,主持。
(2)福建省科学技术厅,福建省自然科学基金项目(青创项目), 2020J05071,泛素连接酶RNF38介导ACTN4泛素化调控鼻咽癌细胞增殖和凋亡的分子机制研究, 2020-08至2023-08, 4万元,在研,主持。
(3)福建省科学技术厅,福建省科技创新联合资金项目(引领项目), 2019Y9037, RNF38调控EPLIN对抑制 鼻咽癌转移的作用及机制研究, 2020-09至2023-08, 15万元,在研,主持。
(4)福建医科大学,福建医科大学启航基金项目, 2019QH1192,血浆EB病毒miR-BART8-3p检测在辅助鼻咽 癌诊疗的临床意义研究, 2020-04至2023-04, 5万元,在研,主持。
(5)国家自然科学基金委员会,面上项目, 82173051, YY1调控超级增强子驱动FAM201A过表达介导食管鳞 癌放射抗拒的分子机制研究, 2022-01-01至2025-12-31, 54.7万元,在研,参与。
(6)国家自然科学基金委员会,面上项目, 81972717, SOX4调控超级增强子驱动EBV BART过表达促进鼻咽 癌转移的分子机制研究, 2020-01-01至2023-12-31, 55万元,在研,参与。
(7)国家自然科学基金委员会,联合基金项目, U1705282,新型光/声动力纳米药物的构建、双模态成像与 协同抗肿瘤效应, 2018-01-01至2021-12-31, 204万元,结题,参与。
获奖经历
1.多次在国内知名的中国临床肿瘤学会(CSCO)、中国肿瘤学大会(CCO)等进行壁报展示和交流。
2.获得福建省第二十一届肿瘤学大会“优秀论文”
近五年发表的主要论文
1.Lin Cheng; Zong Jingfeng; Lin Wangsong; Wang Minghui; Xu Yuanji; Zhou Rui; Lin Shaojun; Guo Qiaojun; Chen Honglin; Ye Yunbin; Zhang Bin; Pan Jianji; EBV-miR-BART8-3p induces epithelial-mesenchymal transition and promotes metastasis of nasopharyngeal carcinoma cells through activating NF-κB and Erk1/2 pathways, Journal of Experimental & Clinical Cancer Research, 2018, 37(1): 283 (中科院一区,IF=5.646,Web of Science被引频次52次)
2.Lin Cheng; Lin Keyu; Zhang Bin; Su Ying; Guo Qiaojuan; Lu Tianzhu; Xu Yuanji; Lin Shaojun; Zong Jingfeng; Pan Jianji ; Plasma Epstein-Barr Virus MicroRNA BART8-3p as a Diagnostic and Prognostic Biomarker in Nasopharyngeal Carcinoma, The Oncologist, 2022 (中科院二区,IF=5.8362)
3.Lin Cheng; Li Meifang; Lin Na; Zong Jingfeng; Pan Jianji; Ye Yunbin ; RNF38 suppress growth and metastasis via ubiquitination of ACTN4 in nasopharyngeal carcinoma, BMC Cancer, 2022, 22(1): 549 (中科院二区,IF=4.638)
4.Lin Cheng; Lin sheng; Zhu lili; Lin shaojun; Pan jianji; Xu yun ; Optimizing the treatment mode for de novo metastatic nasopharyngeal carcinoma with bone-only metastasis, BMC Cancer, 2022, 22: 35 (中科院二区,IF=4.638)
5.Lin Cheng; Chen Xiong; Li Meifang; Liu Jingnan; Qi Xingfeng; Yang Wenting; Zhang Hairong; Cai Zhongfu; Dai Yun; Ouyang Xuenong; Programmed Death-Ligand 1 Expression Predicts Tyrosine Kinase Inhibitor Response and Better Prognosis in a Cohort of Patients With Epidermal Growth Factor Receptor Mutation- Positive Lung Adenocarcinoma, Clinical Lung Cancer, 2015, 16(5): 25-35 (中科院三区,IF=3.029,Web of Science被引频次83次)
6.Lin Cheng; Lin Sheng; Guo Qiao-Juan; Lin Sheng; Guo Qiao-Juan; Zong Jing-Feng; Lu Tian-Zhu; Lin Na; Lin Shao-Jun; Zong Jing-Feng; Lu Tian-Zhu; Lin Na; Lin Shao-Jun; Pan Jian-Ji; Systemic immune-inflammation index as a prognostic marker in patients with newly diagnosed metastatic nasopharyngeal carcinoma: a propensity score-matched study. Transl Cancer Res, 8(5), 2089-2098(中科院四区,IF=0.986)
7.Chan Sik Kwan;Lin Cheng; Huang Shao Hui; Chau Tin Ching; Guo Qiao Juan; O'Sullivan Brian; Lam Ka On; Chau Sze Chun; Chan Sum Yin; Tong Chi Chung; Vardhanabhuti Varut; Kwong Dora Lai Wan; So Tsz Him; Ng Chor Yi; Leung To Wai; Luk Mai Yee; Lee Anne Wing Mui; Choi Horace Cheuk Wai; Pan Jian Ji; Lee Victor Ho Fun; Refining TNM-8 M1 categories with anatomic subgroups for previously untreated de novo metastatic nasopharyngeal carcinoma. Oral Oncol, 2022, 126: 105736(中科院一区,IF=5.972)
8.Zong Jingfeng; Ji Pengjie;Lin Cheng; Zhang Ruiting; Chen Yuebing; Lu Qiongjiao; Peng Xiane; Pan Jianji; Lin Shaojun; Plasma Epstein-Barr viral DNA load after completion of two cycles of induction chemotherapy predicts outcomes for patients with advanced-stage nasopharyngeal carcinoma. Oral Oncol, 131(undefined), 105972(中科院一区,IF=5.972)
9.宗井凤,郑瑜宏,林城,陈燕,陈传本,潘建基,林少俊.血浆EBV DNA监测鼻咽癌治疗疗效意义.中华放射肿瘤学杂志,2019,28(12):881-884
10.Lu Tianzhu; Guo Qiaojuan; Lin Keyu; Chen Honglin; Chen Yixin; Xu Yuanji;Lin Cheng; Su Ying; Chen Yan; Chen Mengyuan; Zheng Yuhong; Ye Yunbin; Lin Shaojun; Zong Jingfeng; Pan Jianji; Circulating Epstein-Barr virus microRNAs BART7-3p and BART13-3p as novel biomarkers in nasopharyngeal carcinoma. Cancer Sci, 2020, 111(5), 1711-1723(中科院二区,IF=6.7160)
11.Xu Yuan-Ji; Zhou Rui; Zong Jing-Feng; Lin Wan-Song; Tong Shuang; Guo Qiao-Juan;Lin Cheng; Lin Shao-Jun; Chen Yi-Xin; Chen Mei-Ru; Chen Hong-Lin; Ye Yun-Bin; Pan Jian-Ji; Epstein-Barr virus-coded miR-BART13 promotes nasopharyngeal carcinoma cell growth and metastasis via targeting of the NKIRAS2/NF-κB pathway. Cancer Lett, 2019, 447(undefined), 33-40(中科院一区,IF= 7.3603)
获得专利
1.林城;一种放射治疗用定位固定架, 2021-12-17,中国, ZL 2021 2 0241110.2
2.林城;一种用于放射治疗的报警装置, 2021-12-17,中国, ZL 2021 2 0338681.8
3.林城;李梅芳;郑丽雅;林昇;林灿阳;一种肿瘤放疗头颈保护装置, 2022-12-09,中国, ZL 2022 2 0532154.5