基本信息
职称:副主任技师
研究方向:肿瘤免疫
联系电话:18960766320
电子邮件:zzf2004312@qq.com,zzf2004312@fjzlhospital.com
个人简介
周智锋,男,肿瘤学硕士。福建医科大学基础医学院、福建省肿瘤医院免疫学研究室,福建医科大学、福州大学硕士生导师。主要从事肿瘤免疫的基础与临床转化,医工合作。
社会兼职
福建省肿瘤转化医学重点实验室主要成员;福建省医学会肝病学分会肝病转化医学学组委员;福建省肿瘤医院伦理委员;福建省海峡肿瘤防治肿瘤绿色治疗委员;《中华肿瘤防治杂志》青年编委;中国抗癌协会肿瘤营养专业委员会肿瘤免疫营养学组委员;亚太医学生物免疫学会肿瘤学分会委员。
主要科研项目及获奖经历
主持或参与国家级、省、厅级课题20余项。发表SCI等中外文40余篇,书籍《肿瘤免疫营养》。2018年福建省抗癌协会科技三等奖。
近5年发表文章
1.周智锋,柳硕岩,李洁羽,陈明秋,林辉,陈宇杰,陈伟杰,林军鹏,周航,郑庆丰.IL-21和CCL19修饰可提高NKP30 CAR-T细胞对肺癌的杀伤效率并促进其肿瘤浸润[J].南方医科大学学报,2024,44(10):1926-1936。(卓越期刊)
2.Zhifeng Zhou,Tianchuan Li,Jieyu Li,Wansong Lin,Qingfeng Zheng. Exosomal transfer of HCC-derived miR-17-5p downregulates NK cell function by targeting RUNX1-NKG2D axis. Int Immunopharmacol. 2024 Jul 30:136:112361. doi: 10.1016/j.intimp.2024. 112361. Epub 2024 May 30.
3. Zhifeng Zhou;Jieyu Li; Jingwen Hong; Shuping Chen; Mingshui Chen; Ling Wang; Wansong Lin; Yunbin Ye ; Interleukin-15 and chemokine ligand 19 enhance cytotoxic effects of chimeric antigen receptor T cells using zebrafish xenograft model of gastric cancer, Frontiers in Immunology, 2022, 13.
4.Tian‐Chuan Li; Nai‐Jie Chen; Yun‐Ying Chen; Bing‐Jing He;Zhi‐Feng Zhou; Solasonine induces apoptosis of the SGC‐7901 human gastric cancer cell line in vitro via the mitochondriamediated pathway, Journal of Cellular and Molecular Medicine, 2022, 26(12) .(通讯作者)
5.Zhou, Zhi-Feng;Wei, Zhi; Yao, Jin-Chan; Liu, Shuo-Yan; Wang, Feng; Wang, Zhen; Chen,Xiao-Feng; Lin, Hui; Ye, Yunbin; Zheng, Qing-Feng ; CircRNA_102179 promotes the proliferation,migration and invasion in non-small cell lung cancer cells by regulating miR-330-5p/HMGB3 axis. Pathology Research and Practice, 2020, 216(11): 0-153144 .
6.Zhou, Zhi-Feng; Peng, Feng; Li, Jie-Yu; Ye, Yun-Bin; Intratumoral IL-12 Gene Therapy Inhibits Tumor Growth In A HCC-Hu-PBL-NOD/SCID Murine Model., OncoTargets and Therapy, 2019, 12: 7773-7784.